The codeine in acetaminophen and codeine phosphate tablets could enhance the frequency of seizures in patients with seizure Problems, and should increase the danger of seizures happening in other clinical configurations related to seizures.
Tend not to take acetaminophen and codeine phosphate tablets Should you have: serious asthma, hassle respiration, or other lung problems. a bowel blockage or narrowing on the tummy or intestines. Formerly experienced an allergic response to codeine or acetaminophen.
Even though the chance of habit in almost any particular person is not known, it may happen in individuals properly prescribed acetaminophen and codeine phosphate tablets. Habit can take place at recommended dosages and In the event the drug is misused or abused.
The severity of the withdrawal signs knowledgeable will depend upon the degree of Actual physical dependence as well as the dose in the antagonist administered. If a decision is made to take care of significant respiratory depression within the physically dependent affected individual, administration of your antagonist really should be started with care and by titration with lesser than regular doses on the antagonist.
To reduce the potential risk of dizziness and lightheadedness, get up little by little when soaring from the sitting or lying position.
Fast discontinuation has also been linked to tries to click here find other resources of opioid analgesics, which may be read more confused with drug-in search of for abuse.
Neonatal Opioid Withdrawal get more info Syndrome Tell feminine people of reproductive likely that use of check here acetaminophen and codeine phosphate tablets for an extended stretch of time all through pregnancy may end up in neonatal opioid withdrawal syndrome, which may be lifetime-threatening Otherwise regarded and handled (see PRECAUTIONS, Pregnancy).
An opioid pain drugs that will place you at risk for overdose and Demise. Even though you take your dose effectively as prescribed, you happen to be in danger for opioid habit, abuse, and misuse that can result in Dying.
To reduce the chance of respiratory depression, right dosing and titration of acetaminophen and codeine phosphate tablets are important (see DOSAGE AND ADMINISTRATION).
People who will be extremely-rapid metabolizers of codeine because of a CYP450 2D6 polymorphism, will convert codeine a lot more fast and absolutely to morphine causing unexpectedly high morphine levels, which can be lifetime-threatening.
Use of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with acetaminophen and codeine phosphate tablets requires careful consideration of the effects to the guardian drug, codeine, and also the active metabolite, morphine.
Stay clear of giving acetaminophen and codeine phosphate tablets to young children concerning 12 to 18 decades of age who've risk aspects for respiration complications like obstructive rest apnea, being overweight, or fundamental lung troubles.
Speak with your Health care supplier about naloxone, a drugs for the unexpected emergency procedure of an opioid overdose.
This mixture medication is read more utilized to help relieve gentle to reasonable soreness. It contains an opioid ache reliever (codeine) in addition to a non-opioid pain reliever (acetaminophen). Codeine functions inside the brain to alter how Your entire body feels and responds to discomfort. Acetaminophen also can cut down a fever. View Extra